What is Gnotobiology in Lab Animal Science?
Over the past 20 years, transgenic mice have become the principal laboratory animal model used in biomedical research. Within this…
Ducted cabinet for animal facilities? What to know (part 5)
Last chapter of the series dedicated to ducted cabinets and what are the important things to know about them when…
Ducted cabinet for animal facilities? What to know (part 4)
If toxic gases and vapors are expected to be present during the use of the BSC, the CDC/NIH states, “Type…
Sterile water for germ free mice: it has never been so easy!
Thinking about germ free facilities and water sterilisation the first thing that comes to mind is the large Pyrex bottle…
Ducted cabinet for animal facilities? What to know (part 3)
Connection of a Class II/A2 Biosafety Cabinet to a Building Exhaust System. In 2010, the National Sanitation Foundation (NSF) and…
The microbiological monitoring of Germ free mice
“The so-called germ-free animal is germ free only within the limits of the techniques used to determine its freedom from…
Plastic cages for gnotobiotic and germ free mice: How to select the right material
When it comes to selecting a plastic cage to be used in a particular application (like Gnotobiotic facilities), there are…
Decontamination of the Air Handling Unit (AHU)
The Air Handling Unit (AHU) is an essential tool to guarantee the welfare of germ free animals. To ensure the…
Modelling gut-brain interactions in gnotobiotic mouse models
Understanding the molecular mechanisms underlying gut-brain interactions has become one of the central topics in the neuroscience field. In fact,…
Gnotobiotic facility: How do you decontaminate a Biosafety Cabinet (BSC)? (part.3)
The last total decontamination for Biosafety Cabinet (surface + interior parts) in a Gnotobiotic facility , officially reported in the…
Recent Articles
- Gnotobiotic facilities: writing inside isolators 4 April 2022
- Germ-free cage sterilization 24 January 2022
- Microbiota and its importance in aging 25 October 2021
- Procedural diversity and technical choices working with gnotobiotic mice in IVCs. (part 2) 27 September 2021
- Procedural diversity and technical choices working with gnotobiotic mice in IVCs. (part 1) 30 August 2021
DVC – Digital Ventilated Cage for digital vivarium

The DVC® is capable to provide novel insights and enhance animal welfare checks thanks to the automatic data collection directly from the cage level. Specifically designed DVC® board enables different benefits for the researchers and vivarium people.