Gnotobiotic facility: How do you decontaminate a Biosafety Cabinet (BSC)? (part.2)
Another total decontamination (surface + interior parts) method for Biosafety Cabinet (BSC) in a gnotobiotic facility is the formaldehyde fumigation…
Gnotobiotic facility: How do you decontaminate a Biosafety Cabinet (BSC)? (part.1)
There are, mainly, two different Biosafety Cabinet (BSC) decontamination types for the safety of a gnotobiotic facility. Surface decontamination which…
Housing of germ free animals
Germ free mice, also called Axenic, are animals free of all foreign life forms apart from itself (as determined within…
Ducted cabinet for animal facilities? What to know (part 2)
When exhausting a cabinet to atmosphere, three options are available for consideration: Hard ducting with constant room extract Hard ducting…
Ducted cabinet for animal facilities? What to know (part 1)
All Class II, Type A2 Biosafety Cabinets are designed to recirculate their HEPA filtered exhaust air back into the laboratory….
Sterilization of diets for Germ Free rodents: treatment, monitoring and validation
The use of sterile diets is a must in maintaining germ free or gnotobiotic rodents. There are basically two methods…
The concept of standardization controversy
The concept of standardization in the field of research with laboratory animals is today a cause of controversy between different…
Viruses and microbiome interaction in gnotobiotic mice.
The idea that there is a four-factor interaction when it comes to the entry of viruses into organisms now seems…
Standard Operating Procedures (SOP) and activities to be defined when setting up an ISOPOSITIVE equipped facility.
The development of standard operating procedures for efficient activities in laboratory animal facilities is a normal practice, well known by…
THE SERVICE CAGE: Autoclavable container ready to use!
The service cage is an autoclavable container used for the transfer of equipment and materials useful for carrying out different…
Recent Articles
- Gnotobiotic facilities: writing inside isolators 4 April 2022
- Germ-free cage sterilization 24 January 2022
- Microbiota and its importance in aging 25 October 2021
- Procedural diversity and technical choices working with gnotobiotic mice in IVCs. (part 2) 27 September 2021
- Procedural diversity and technical choices working with gnotobiotic mice in IVCs. (part 1) 30 August 2021
DVC – Digital Ventilated Cage for digital vivarium

The DVC® is capable to provide novel insights and enhance animal welfare checks thanks to the automatic data collection directly from the cage level. Specifically designed DVC® board enables different benefits for the researchers and vivarium people.