Sterile water for germ free mice: it has never been so easy!
Thinking about germ free facilities and water sterilisation the first thing that comes to mind is the large Pyrex bottle...
The microbiological monitoring of Germ free mice
“The so-called germ-free animal is germ free only within the limits of the techniques used to determine its freedom from...
Plastic cages for gnotobiotic and germ free mice: How to select the right material
When it comes to selecting a plastic cage to be used in a particular application (like Gnotobiotic facilities), there are...
Decontamination of the Air Handling Unit (AHU)
The Air Handling Unit (AHU) is an essential tool to guarantee the welfare of germ free animals. To ensure the...
Modelling gut-brain interactions in gnotobiotic mouse models
Understanding the molecular mechanisms underlying gut-brain interactions has become one of the central topics in the neuroscience field. In fact,...
Housing of germ free animals
Germ free mice, also called Axenic, are animals free of all foreign life forms apart from itself (as determined within...
Sterilization of diets for Germ Free rodents: treatment, monitoring and validation
The use of sterile diets is a must in maintaining germ free or gnotobiotic rodents. There are basically two methods...
The concept of standardization controversy
The concept of standardization in the field of research with laboratory animals is today a cause of controversy between different...
Viruses and microbiome interaction in gnotobiotic mice.
The idea that there is a four-factor interaction when it comes to the entry of viruses into organisms now seems...
Standard Operating Procedures (SOP) and activities to be defined when setting up an ISOPOSITIVE equipped facility.
The development of standard operating procedures for efficient activities in laboratory animal facilities is a normal practice, well known by...
The DVC® is capable to provide novel insights and enhance animal welfare checks thanks to the automatic data collection directly from the cage level. Specifically designed DVC® board enables different benefits for the researchers and vivarium people.