The involvement of microbiome in neurological disorders: an update
M.G. Staff,
3 years ago
1 min read
A recent Nature article emphasized how microbiome research is becoming central to understanding the development of neurological disorders (Ref. https://www.nature.com/articles/d41586-021-00260-3)...
What is Gnotobiology in Lab Animal Science?
M.G. Staff,
4 years ago
1 min read
Over the past 20 years, transgenic mice have become the principal laboratory animal model used in biomedical research. Within this...
Plastic cages for gnotobiotic and germ free mice: How to select the right material
M.G. Staff,
4 years ago
2 min read
When it comes to selecting a plastic cage to be used in a particular application (like Gnotobiotic facilities), there are...
Decontamination of the Air Handling Unit (AHU)
M.G. Staff,
4 years ago
1 min read
The Air Handling Unit (AHU) is an essential tool to guarantee the welfare of germ free animals. To ensure the...
Modelling gut-brain interactions in gnotobiotic mouse models
M.G. Staff,
4 years ago
1 min read
Understanding the molecular mechanisms underlying gut-brain interactions has become one of the central topics in the neuroscience field. In fact,...
Gnotobiotic facility: How do you decontaminate a Biosafety Cabinet (BSC)? (part.3)
M.G. Staff,
4 years ago
2 min read
The last total decontamination for Biosafety Cabinet (surface + interior parts) in a Gnotobiotic facility , officially reported in the...
Gnotobiotic facility: How do you decontaminate a Biosafety Cabinet (BSC)? (part.2)
M.G. Staff,
4 years ago
1 min read
Another total decontamination (surface + interior parts) method for Biosafety Cabinet (BSC) in a gnotobiotic facility is the formaldehyde fumigation...
Gnotobiotic facility: How do you decontaminate a Biosafety Cabinet (BSC)? (part.1)
M.G. Staff,
4 years ago
1 min read
There are, mainly, two different Biosafety Cabinet (BSC) decontamination types for the safety of a gnotobiotic facility. Surface decontamination which...
Housing of germ free animals
M.G. Staff,
4 years ago
1 min read
Germ free mice, also called Axenic, are animals free of all foreign life forms apart from itself (as determined within...
Sterilization of diets for Germ Free rodents: treatment, monitoring and validation
M.G. Staff,
4 years ago
1 min read
The use of sterile diets is a must in maintaining germ free or gnotobiotic rodents. There are basically two methods...
Recent Articles
- Gnotobiotic facilities: writing inside isolators 4 April 2022
- Germ-free cage sterilization 24 January 2022
- Microbiota and its importance in aging 25 October 2021
- Procedural diversity and technical choices working with gnotobiotic mice in IVCs. (part 2) 27 September 2021
- Procedural diversity and technical choices working with gnotobiotic mice in IVCs. (part 1) 30 August 2021
DVC – Digital Ventilated Cage for digital vivarium
The DVC® is capable to provide novel insights and enhance animal welfare checks thanks to the automatic data collection directly from the cage level. Specifically designed DVC® board enables different benefits for the researchers and vivarium people.