Microbiota and its importance in aging
Gut microbiota is increasingly an important regulator of host immunity and brain health. Aging processes lead to important alterations in...
Procedural diversity and technical choices working with gnotobiotic mice in IVCs. (part 2)
We left off last time with the following question: Which disinfectant should we use to obtain a decontamination of the...
Procedural diversity and technical choices working with gnotobiotic mice in IVCs. (part 1)
The use of IVCs cages in the context of the maintenance of Germ-Free or flora associated rodents required, on the...
The involvement of microbiome in neurological disorders: an update
A recent Nature article emphasized how microbiome research is becoming central to understanding the development of neurological disorders (Ref. https://www.nature.com/articles/d41586-021-00260-3)...
What is Gnotobiology in Lab Animal Science?
Over the past 20 years, transgenic mice have become the principal laboratory animal model used in biomedical research. Within this...
The microbiological monitoring of Germ free mice
“The so-called germ-free animal is germ free only within the limits of the techniques used to determine its freedom from...
Modelling gut-brain interactions in gnotobiotic mouse models
Understanding the molecular mechanisms underlying gut-brain interactions has become one of the central topics in the neuroscience field. In fact,...
The concept of standardization controversy
The concept of standardization in the field of research with laboratory animals is today a cause of controversy between different...
Viruses and microbiome interaction in gnotobiotic mice.
The idea that there is a four-factor interaction when it comes to the entry of viruses into organisms now seems...
The DVC® is capable to provide novel insights and enhance animal welfare checks thanks to the automatic data collection directly from the cage level. Specifically designed DVC® board enables different benefits for the researchers and vivarium people.