Gnotobiotic facilities: writing inside isolators
Written by M.G Staff and Joana Bom (Axenic/Gnotobiology and Mouse Facility Manager – Instituto Gulbenkian de Ciência, Portugal) While nowadays...
Germ-free cage sterilization
On the subject of germ-free animals and equipment used for housing the first word that comes to mind is “sterility”....
Microbiota and its importance in aging
Gut microbiota is increasingly an important regulator of host immunity and brain health. Aging processes lead to important alterations in...
Procedural diversity and technical choices working with gnotobiotic mice in IVCs. (part 2)
We left off last time with the following question: Which disinfectant should we use to obtain a decontamination of the...
Procedural diversity and technical choices working with gnotobiotic mice in IVCs. (part 1)
The use of IVCs cages in the context of the maintenance of Germ-Free or flora associated rodents required, on the...
UV Light and its exclusive use in Biosafety Cabinets of Gnotobiotic facilities (Part 2)
When working with germ-free or axenic mice we would like to point out that the germicidal lamps are used for...
UV Light and its exclusive use in Biosafety Cabinets of Gnotobiotic facilities (Part 1)
In many germ-free or gnotobiotic facilities it is possible to find Biosafety Cabinets with UV lamps. UV lamps operate in...
Hydrogen peroxide: two main delivery methods for Gnotobiotic Facilities
The constantly growing research front of Gnotobiology requires more and more alternative bio decontamination methods to keep the germ- free...
The involvement of microbiome in neurological disorders: an update
A recent Nature article emphasized how microbiome research is becoming central to understanding the development of neurological disorders (Ref. https://www.nature.com/articles/d41586-021-00260-3)...
Inexpensive shipment of germ-free and Gnotobiotic animals
Shipping germ-free or gnotobiotic animals is a challenge with many variables to control. Currently the most common option for shipping...
The DVC® is capable to provide novel insights and enhance animal welfare checks thanks to the automatic data collection directly from the cage level. Specifically designed DVC® board enables different benefits for the researchers and vivarium people.